PUBLICATIONS
2023
Synaptic BMAL1 Phosphorylation Controls Circadian Hippocampal Plasticity
Barone I, Gilette, NM, Hawks-Mayer H, Handy J, Zhang KJ, Chifamba FF, Mostafa E, Johnson-Venkatesh EM, Sun Y, Gibson JM, Rotenberg A, Umemori H, Tsai PT, Lipton JO.
Science Advances 2023 Oct 27;9(43):eadj1010. doi: 10.1126/sciadv.adj1010. Epub 2023 Oct 25.
PMID: 37878694
Defining diurnal fluctuations in mouse choroid plexus and CSF at high molecular, spatial, and temporal resolution
Fame RM, Kalugin PN, Petrova B, Xu H, Soden PA, Shipley FB, Dani N, Grant B, Pragana A, Head JP, Gupta S, Shannon ML, Chifamba FF, Hawks-Mayer H, Vernon A, Gao F, Zhang Y, Holtzman MJ, Heiman M, Andermann ML, Kanarek N, Lipton JO, Lehtinen MK.
Nature Communications 2023 Jun 22;14(1):3720. doi: 10.1038/s41467-023-39326-3.
PMID: 37349305
2019
Deletion of neuronal GLT-1 in mice reveals its role in synaptic glutamate homeostasis and mitochondrial function.
McNair LF, Andersen JV, Aldana B, Hohnholt MC, Nissen JD, Sun Y, Fischer KD, Sonnewald U, Nyberg N, Webster SC, Kapur K, Rimmele TS, Barone I, Hawks-Mayer H, Lipton JO, Hodgson NW, Aoki CJ, Rosenberg PA, Waagepetersen HS.
Journal of Neuroscience 2019 Mar 29. pii: 0894-18. doi: 10.1523/JNEUROSCI.0894-18.2019.
PMID: 30926746
Mechanisms of sleep and circadian ontogeny through the lens of neurodevelopmental disorders.
Barone I, Hawks-Mayer H, Lipton JO.
Neurobiol Learn Mem. 2019 Jan 19. pii: S1074-7427(19)30011-5. doi: 10.1016/j.nlm.2019.01.011.
PMID: 30668981
2018
Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups.
Archer TC, Ehrenberger T, Mundt F, Gold MP, Krug K, Mah CK, Mahoney EL, Daniel CJ, LeNail A, Ramamoorthy D, Mertins P, Mani DR, Zhang H, Gillette MA, Clauser K, Noble M, Tang LC, Pierre-François J, Silterra J, Jensen J, Tamayo P, Korshunov A, Pfister SM, Kool M, Northcott PA, Sears RC, Lipton JO, Carr SA, Mesirov JP, Pomeroy SL, Fraenkel E.
Cancer Cell. 2018 Sep 10;34(3):396-410.e8. doi: 10.1016/j.ccell.2018.08.004.
PMID: 30205044
2017
mGluR5 Modulation of Behavioral and Epileptic Phenotypes in a Mouse Model of Tuberous Sclerosis Complex
Kelly, E, Schaeffer, SM, Dhamne, SC, Lipton JO, Lindemann, L, Honer, M, Jaeschke, G, Super, CE, Lammers, SH, Modi, ME, Silverman, JL, Dreier, JR, Kwiatkowski, DJ, Rotenberg, A, Sahin, M.
Neuropsychopharmacology. 2017 Dec 5. doi: 10.1038/npp.2017.295.
PMID: 29206810
Aerrant Proteostasis of BMAL1 Underlies Circadian Abnormalities in a Paradigmatic mTOR-opathy
Lipton JO, Boyle LM, Yuan ED, Hochstrasser KJ, Chifamba FF, Nathan A, Tsai PT, Davis F, Sahin M. (*co-corresponding author)
Cell Reports. 2017 Jul 25;20(4):868-880. doi: 10.1016/j.celrep.2017.07.008.
PMID: 28746872
Neural Circuitry of Wakefulness and Sleep.
Scammell TE, Arrigoni E, and Lipton JO.
Neuron. 2017 Feb 22;93(4):747-765. doi: 10.1016/j.neuron.2017.01.014.
PMID: 28231463
2016
Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex
Ebrahimi-Fakhari D, Saffari A, Wahlster L, DiNardo A, Turner D, Lewis TL Jr, Conrad C, Rothberg JM, Lipton JO, Kölker S, Hoffmann GF, Han MJ, Polleux F, Sahin M.
Cell Reports. 2016 Oct 18;17(4):1053-1070. doi: 10.1016/j.celrep.2016.09.054.
PMID: 27760312
2015
The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation.
Lipton JO, Yuan ED, Boyle LM, Ebrahimi-Fakhari D, Kwiatkowski E, Nathan A, Güttler T, Davis F, Asara JM, Sahin M.
Cell. 2015 May 21; 161(5):1138-51. doi: 10.1016/j.cell.2015.04.002.
PMID: 25981667
2014
The Neurology of mTOR.
Lipton JO and Sahin M.
Neuron. 2014 Oct 22;84(2):275-91. doi: 10.1016/j.neuron.2014.09.034.
PMID: 25374355